S-Stem Scholar Jaira Munoz Zavala's Blog

This semester, I'm focusing on CHIT1.  CHIT1 is a gene and encodes a protein called Chitotriosidase-1, and is a member of the chitinase family. This is selectively expressed in activated tissue macrophages. As a biomarker  (it indicates the  severity or presence of some disease state) is the best  to monitor Gaucher disease from the three most commonly used. Also, it is a marker for macrophage activation in acute ischemic stroke. Chromosomal location  Cytogenetic Location: 1q32.1. 1q    = The long (q) arm of the chromosome 1 32.1 =  It is the position in the arm. Molecular Location: base pairs 203,216,079 to 203,229,673  Data and Picture Reference: Genetics Home Reference.  August 17th, 2020. CHIT1 gene, Chitinase1. Retrieved from: https://ghr.nlm.nih.gov/gene/CHIT1#resources Function:  Chitinases wo rks in both innate and adaptive immunity.  They are necessary for the following functions: Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematode