Protein: Q13231 (CHIT1)
This semester, I'm focusing on CHIT1. CHIT1 is a gene and encodes a protein called Chitotriosidase-1, and is a member of the chitinase family. This is selectively expressed in activated tissue macrophages. As a biomarker (it indicates the severity or presence of some disease state) is the best to monitor Gaucher disease from the three most commonly used. Also, it is a marker for macrophage activation in acute ischemic stroke. Chromosomal location Cytogenetic Location: 1q32.1. 1q = The long (q) arm of the chromosome 1 32.1 = It is the position in the arm. Molecular Location: base pairs 203,216,079 to 203,229,673 Data and Picture Reference: Genetics Home Reference. August 17th, 2020. CHIT1 gene, Chitinase1. Retrieved from: https://ghr.nlm.nih.gov/gene/CHIT1#resources Function: Chitinases wo rks in both innate and adaptive immunity. They are necessary for the following functions: Degrades chitin, chitotriose and...